首页>
外国专利>
PROCESS FOR PRODUCING METAL COMPLEXES OF N-BETA- -HYDROXYALKYLTRI-N-CARBOXYALKYL-1,4,7,10- -TETRAAZACYCLODODECANENIC AND N-BETA-HYDROXYALKYLTRI-N- -CARBOXYALKYL-1,4,8,11-TETRAAZACYCLOTETRADODECANENIC DERIVATIVES
PROCESS FOR PRODUCING METAL COMPLEXES OF N-BETA- -HYDROXYALKYLTRI-N-CARBOXYALKYL-1,4,7,10- -TETRAAZACYCLODODECANENIC AND N-BETA-HYDROXYALKYLTRI-N- -CARBOXYALKYL-1,4,8,11-TETRAAZACYCLOTETRADODECANENIC DERIVATIVES
A process for the preparation of metal complexes of N-beta-hydroxyalkyl tri-N-carboxyalkyl-1,4,7,10-tetraazacyclododecane and N-beta-hydroxyalkyl tri-N-carboxy-alkyl-1,4,8,11-tetraazacyclotetradecanoic is disclosed. the compounds of formula (I) in which the compound of formula (II) prepared from 1,4,7,10-tetraazacyclododecane or 1,4,8,11-tetraazacyclotetradecane is reacted with the corresponding epoxide, the compound obtained is saponified and left to react with a carboxy compound and reacting the product with an oxide or salt of the respective metal.
展开▼