首页> 外国专利> PROCESS FOR PRODUCING METAL COMPLEXES OF N-BETA- -HYDROXYALKYLTRI-N-CARBOXYALKYL-1,4,7,10- -TETRAAZACYCLODODECANENIC AND N-BETA-HYDROXYALKYLTRI-N- -CARBOXYALKYL-1,4,8,11-TETRAAZACYCLOTETRADODECANENIC DERIVATIVES

PROCESS FOR PRODUCING METAL COMPLEXES OF N-BETA- -HYDROXYALKYLTRI-N-CARBOXYALKYL-1,4,7,10- -TETRAAZACYCLODODECANENIC AND N-BETA-HYDROXYALKYLTRI-N- -CARBOXYALKYL-1,4,8,11-TETRAAZACYCLOTETRADODECANENIC DERIVATIVES

机译:生产N-BETA-羟基羟基三-N-羧基烷基-1,4,7,10-四氮杂十二碳和N-BETA羟基三氮杂-羧基--1,4,8,11-四十二碳三烯的金属络合物的方法

摘要

A process for the preparation of metal complexes of N-beta-hydroxyalkyl tri-N-carboxyalkyl-1,4,7,10-tetraazacyclododecane and N-beta-hydroxyalkyl tri-N-carboxy-alkyl-1,4,8,11-tetraazacyclotetradecanoic is disclosed. the compounds of formula (I) in which the compound of formula (II) prepared from 1,4,7,10-tetraazacyclododecane or 1,4,8,11-tetraazacyclotetradecane is reacted with the corresponding epoxide, the compound obtained is saponified and left to react with a carboxy compound and reacting the product with an oxide or salt of the respective metal.
机译:一种制备N-β-羟烷基三-N-羧基烷基-1,4,7,10-四氮杂环十二烷和N-β-羟烷基三-N-羧基-烷基-1,4,8,11的金属配合物的方法公开了-四氮杂环十四烷酸。使由1,4,7,10-四氮杂环十二烷或1,4,8,11-四氮杂环十四烷制备的式(II)化合物与相应的环氧化物反应的式(I)化合物被皂化并使其与羧基化合物反应并使产物与相应金属的氧化物或盐反应。

著录项

  • 公开/公告号SK281285B6

    专利类型

  • 公开/公告日2001-02-12

    原文格式PDF

  • 申请/专利权人 SCHERING AKTIENGESELLSCHAFT;

    申请/专利号SK124193A

  • 发明设计人 PLATZEK JOHANNES;GRIES HEINZ;

    申请日1993-11-05

  • 分类号C07D257/02;

  • 国家 SK

  • 入库时间 2022-08-22 01:23:55

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