CORES OF IMMEDIATE RELEASE PADS OF INSOLUBLE MEDICINES THAT HAVE A COVER OF SUSTAINED RELEASE.

摘要

A CONTROLLED RELEASE TABLET IS PRESENTED FOR ORAL ADMINISTRATION THAT HAS A TABLET NUCLEUS THAT INCLUDES A THERAPEUTICALLY ACTIVE, INSOLUBLE AGENT THAT HAS A LOWER OR AQUOUS WATER SOLUBILITY AROUND 5 MG / ML IN A SUFFICIENT AMOUNT. THE NUCLEO PROVIDES THE FAST RELEASE OF SUCH THERAPEUTICALLY ACTIVE AGENT AFTER ITS EXPOSURE TO WATER SOLUTIONS. THE NUCLEO OF THE TABLET IS COVERED WITH A CONTROLLED RELEASE COVERING THAT ALLOWS THE SUSTAINED RELEASE OF SUCH THERAPEUTICALLY ACTIVE AGENT WHEN SUCH COVERED TABLET IS EXPOSED TO WATER SOLUTIONS.