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Method of analyzing data from a circulating blood viscometer for determining absolute and effective blood viscosity

机译:分析来自循环血液粘度计的数据以确定绝对和有效血液粘度的方法

摘要

A method is provided for detecting interactions in the circulating blood of a living being caused by external factors by analyzing the viscosity of the living being's circulating blood. The method utilizes a blood viscosity measuring system that monitors the change in height of two, oppositely-moving, columns of blood from the circulating blood of a patient and, given the dimensions of a capillary tube through which the blood flows, determines the blood viscosity over a range of shear rates, especially low shear rates. The system includes a tube set that includes a pair of riser tubes, a capillary tube of predetermined dimensions that is coupled between the riser tubes and a valve mechanism for controlling the circulating flow of blood from the patient into the riser tubes. Respective sensors monitor the movement of the columns of blood in each of the riser tubes and an associated microprocessor analyzes these movements, along with the predetermined dimensions of the capillary tube to determine the viscosity of the patient's circulating blood. A first viscosity profile is determined over a first shear rate range and a second viscosity profile is determined over the first shear rate range and a second shear rate range. The method utilizes the relationship of these two viscosity profiles, as well as with respect to a horizontal line, to detect the interactions in the circulating blood of a living being caused by the external factors. Furthermore, the tube set can then be pivoted clockwise and/or counterclockwise for measuring platelet aggregation and red blood cell deformability. In addition, a method and apparatus for determining the yield stress of the blood is discussed, as well as a method for determining the effects of drugs designed to treat a condition of the living being.
机译:提供了一种通过分析生物体循环血液的粘度来检测生物体循环血液中由外部因素引起的相互作用的方法。该方法利用血液粘度测量系统,该系统监视来自患者循环血液的两根反向移动的血液柱的高度变化,并在给定血液流经的毛细管尺寸的情况下确定血液粘度在一定范围的剪切速率下,尤其是低剪切速率。该系统包括管组,该管组包括一对立管,连接在立管之间的预定尺寸的毛细管和用于控制血液从患者进入立管的循环流的阀机构。相应的传感器监视每个立管中的血液柱的运动,并且相关的微处理器分析这些运动,以及毛细管的预定尺寸,以确定患者循环血液的粘度。在第一剪切速率范围内确定第一粘度分布,并且在第一剪切速率范围和第二剪切速率范围内确定第二粘度分布。该方法利用这两个粘度曲线的关系以及相对于水平线的关系,来检测由外界因素引起的活体血液循环中的相互作用。此外,然后可以将管组顺时针和/或逆时针枢转以测量血小板聚集和红细胞可变形性。另外,讨论了用于确定血液的屈服应力的方法和设备,以及用于确定设计用于治疗生物状况的药物的效果的方法。

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