Use of igf-i, igfbp-3 and psa to predict the risk of prostate cancer

摘要

It was determined that the analytes IGF-I and IGFBP-3 can be used to predict the risk of incurring prostate cancer when PSA levels are within certain ranges. Thus, the levels of PSA must also be determined in order to determine how these analytes impact risk. It was found that, when PSA is ≤ 3 ng/ml, the risks for IGF-I and IGFBP-3 are additive. When PSA is 10 ng/ml, the level of IGFBP-3 can be used to predict risk.