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Methods of tissue induction using a combination of bone morphogenetic protein and parathyroid hormone-related peptide
Methods of tissue induction using a combination of bone morphogenetic protein and parathyroid hormone-related peptide
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机译:结合骨形态发生蛋白和甲状旁腺激素相关肽的组织诱导方法
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摘要
Compositions of proteins with chondrocyte and cartilaginous tissue inducing activity, as well as method of using those compositions, are disclosed. The compositions comprise one or more proteins of the transforming growth factor- beta (TGF- beta ) superfamily of proteins, particularly bone morphogenetic proteins (BMPs), in combination with parathyroid hormone related polypeptide (PTHrP) or an equivalent PTH-like polypeptide. The compositions and methods are useful in the treatment of osteoarthritis, cartilage defects and in related tissue repair.
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