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Human glial cell line-derived neurotrophic factor promoters, vectors containing same, and methods of screening compounds therewith
Human glial cell line-derived neurotrophic factor promoters, vectors containing same, and methods of screening compounds therewith
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机译:人胶质细胞系衍生的神经营养因子启动子,含有该启动子的载体以及用其筛选化合物的方法
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摘要
The distal and proximal promoters for the human glial cell line-derived neurotrophic factor (GDNF) gene are provided. In addition, constructs comprising a human GDNF promoter and a reporter gene, a vector comprising the construct and a host cell comprising the vector are provided, as is a method for screening compounds capable of modulating the expression of GDNF by stimulating GDNF promoter-directed transcription.
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