首页> 外国专利> MICROENCAPSULATED GENETICALLY ENGINEERED E. COLI DH 5 CELLS FOR THE REMOVAL OF UNDESIRED ELECTROLYTES AND/OR METABOLITES

MICROENCAPSULATED GENETICALLY ENGINEERED E. COLI DH 5 CELLS FOR THE REMOVAL OF UNDESIRED ELECTROLYTES AND/OR METABOLITES

机译：微囊化的基因工程化大肠杆菌DH 5细胞用于去除不需要的电解质和/或代谢产物

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摘要

The present invention relates to a composition for the removal of at least one undesired electrolyte and/or metabolite in a patient, which comprises a genetically engineered iE. coli DH5/i cells microencapsulated in artificial cells to be capable of removing said undesired electrolyte and/or metabolite, wherein said undesired electrolyte is selected from the group consisting of K, Mg, P, Na, Cl and said undesired metabolite is selected from the group consisting of uric acid, cholesterol, bilirubin, and creatinine, wherein said removal of undesired electrolyte and/or metabolite lowers the undesired chemical concentration to a therapeutically acceptable level.

机译：本发明涉及一种用于除去患者体内至少一种不希望的电解质和/或代谢产物的组合物，其包含基因工程改造的E。微囊化在人造细胞中的大肠杆菌DH5细胞能够去除所述不希望的电解质和/或代谢物，其中所述不希望的电解质选自K，Mg，P，Na，Cl，并且所述不希望的代谢物被选择选自尿酸，胆固醇，胆红素和肌酐，其中所述去除不希望的电解质和/或代谢产物将不希望的化学浓度降低到治疗上可接受的水平。

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公开/公告号WO0065030A3

专利类型
公开/公告日2001-01-25

原文格式PDF
申请/专利权人 MCGILL UNIVERSITY;PRAKASH SATYA;CHANG THOMAS M. S.;
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申请/专利号WO2000CA00482
发明设计人 PRAKASH SATYA;CHANG THOMAS M. S.;
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申请日2000-04-27
分类号C12N11/04;A61K35/74;A61K9/50;A61P3/00;
国家 WO
入库时间 2022-08-22 01:19:21

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