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DOSIMETRY FOR CALIFORNIUM-252 BRACHYTHERAPY SOURCES AND ENCAPSULATION, STORAGE, AND CLINICAL DELIVERY THEREOF
DOSIMETRY FOR CALIFORNIUM-252 BRACHYTHERAPY SOURCES AND ENCAPSULATION, STORAGE, AND CLINICAL DELIVERY THEREOF
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机译:用于加州252胸外科手术来源的剂量及其封装,储存和临床运送
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摘要
The present invention discloses a methodology for the characterization and determination of mixed-field dosimetry for 252Cf Applicator Tube (AT)-type medical sources, utilizing ionization chambers, GM counters, and Monte Carlo methods. Unlike the previous methodologies, the present invention discloses a specification of dose to muscle, rather than dose to water, for clinical dosimetry of 252Cf medical sources. A dosimetry protocol, similar to that utilized for ICRU-45, with parameters determined specifically for 252Cf brachytherapy is disclosed. Neutron isodose distributions and data necessary for clinical implementation of 252Cf AT sources are also disclosed herein. Additionally, novel methods for the encapsulation, storage, and delivery/implantation of 252Cf radionuclide sources are disclosed.
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