DETECTION OF POLYPEPTIDE FRAGMENTS AND MODIFIED FORMS OF α1-ANTITRYPSIN FOR EARLY DIAGNOSIS OF INFLAMMATION

摘要

The present invention provides a method for the detection of a carboxyl-terminal proteolytic fragments of α-1-antitrypsin (AAT) or post-translationally modified forms of AAT (for example, oxidized AAT) as an indicator of chronic inflammation. This method is useful for the early diagnosis of chronic inflammation associated with such diseases as atherosclerosis.