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A method for screening for the presence of a genetic defect associated with thrombosis and/or poor anticoagulant response to activated protein C.
A method for screening for the presence of a genetic defect associated with thrombosis and/or poor anticoagulant response to activated protein C.
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机译:一种用于筛选与血栓形成和/或对活化蛋白C的抗凝反应不良相关的遗传缺陷的存在的方法。
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摘要
Method for screening for the presence of a genetic defect associated with thrombosis and/or poor anticoagulant response to activated protein C (APC). The method is directed at detecting one or more mutations at one or more of the cleavage and/or binding sites for APC of Factor V and/or Factor Va or at Factor VIII and/or Factor VIIIa at either nucleic acid or protein level or both.
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