PREPARATION OF DISODIUM ETHYLENEDIAMINE-N,N'-DISUCCINATE

摘要

A process is disclosed for isolating the disodium salt of a mixture of racemic and meso isomers of sodium salts of ethylenediamine-N,N'-disuccinic acid from alkaline aqueous solutions by adjusting the pH of the alkaline solution to from 5 to 10 by addition of an acid, followed by recovery of the solid disodium salt. The mixture of isomers can be prepared by reacting sodium maleate with ethylenediamine in an alkaline aqueous solution. This method is particularly suited to preparing the disodium salt tetrahydrate and avoids the formation of free acid. The final product biodegrades more rapidly than ethylenediamine-N,N,N',N'-tetraacetic acid (EDTA).