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Secretory thyroid stimulating hormone receptor (TSHR), and method for assaying anti-TSHR antibody using the same
Secretory thyroid stimulating hormone receptor (TSHR), and method for assaying anti-TSHR antibody using the same
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机译:分泌型甲状腺刺激激素受体(TSHR),以及使用该受体测定抗TSHR抗体的方法
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摘要
A recombinant soluble human thyroid hormone receptor, comprising an extracellular domain moiety of a human thyroid hormone receptor, or a mutant thereof, being secretory, and having reactivity with an anti-human thyroid stimulating hormone receptor autoantibody; a composition for assaying an anti-human thyroid stimulating hormone receptor antibody, comprising the receptor and a carrier or diluent; a method for assaying an anti-human thyroid stimulating hormone receptor antibody, comprising reacting an anti-human thyroid stimulating hormone receptor antibody with the receptor; and a process for producing a recombinant soluble human thyroid hormone receptor which is secretory and has reactivity with an anti-human thyroid stimulating hormone receptor autoantibody, comprising infecting an insect cell with a recombinant baculovirus introduced with an extracellular domain moiety of a gene encoding a human thyroid hormone receptor or a mutant thereof, and culturing the infected cell.
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