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PHARMACEUTICAL COMPOSITION COMPRISING ENTACAPONE OR NITECAPONE AS WELL AS A CROSS-LINKED CELLULOSE DEIVATIVE
PHARMACEUTICAL COMPOSITION COMPRISING ENTACAPONE OR NITECAPONE AS WELL AS A CROSS-LINKED CELLULOSE DEIVATIVE
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机译:包含恩替卡朋或尼替卡朋以及交联纤维素衍生物的药物组合物
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摘要
The present invention relates to an oral compacted composition comprising entacapone, nitecapone, or a pharmaceutically acceptable salt thereof and croscarmellose sodium. The composition is premised on the discovery that croscarmellose sodium increases the release rate of entacapone or nitecapone from an oral compacted composition. Preferably the amount of croscarmellose sodium in the composition is at least 6% by weight, preferably from about 8% to about 16% by weight, especially from about 10% to about 14% by weight.
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