首页> 外国专利> PHARMACEUTICAL COMPOSITION COMPRISING ENTACAPONE OR NITECAPONE AS WELL AS A CROSS-LINKED CELLULOSE DEIVATIVE

PHARMACEUTICAL COMPOSITION COMPRISING ENTACAPONE OR NITECAPONE AS WELL AS A CROSS-LINKED CELLULOSE DEIVATIVE

机译:包含恩替卡朋或尼替卡朋以及交联纤维素衍生物的药物组合物

摘要

The present invention relates to an oral compacted composition comprising entacapone, nitecapone, or a pharmaceutically acceptable salt thereof and croscarmellose sodium. The composition is premised on the discovery that croscarmellose sodium increases the release rate of entacapone or nitecapone from an oral compacted composition. Preferably the amount of croscarmellose sodium in the composition is at least 6% by weight, preferably from about 8% to about 16% by weight, especially from about 10% to about 14% by weight.
机译:本发明涉及一种口服紧致组合物,其包含entacapone,nitecapone或其药学上可接受的盐和交联羧甲基纤维素钠。所述组合物的前提是发现交联羧甲基纤维素钠增加了口腔致密化组合物中恩他卡朋或尼他卡朋的释放速率。优选地,组合物中交联羧甲基纤维素钠的量为至少6重量%,优选为约8重量%至约16重量%,尤其为约10重量%至约14重量%。

著录项

  • 公开/公告号SI1112065T1

    专利类型

  • 公开/公告日2004-04-30

    原文格式PDF

  • 申请/专利权人 ORION CORPORATION;

    申请/专利号SI19990030508T

  • 发明设计人 VAHERVUO KARI;

    申请日1999-09-13

  • 分类号A61K9/20;A61K31/12;A61K31/16;

  • 国家 SI

  • 入库时间 2022-08-21 23:08:41

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