:-2'-45--3--4-2-11'--2--33- -45--3--2'-33--2--1--4'-2-11'--2- Endothelin Antagonists: N-2'-45-Dimethyl-3-IsoxazolylAminoSulfonyl-4-2-Oxazolyl11'-Biphenyl-2-ylMethyl-N33-trimethylbutanamide And N-45-Dimethyl-3-Isoxazolyl-2'-33-Dimethyl-2-Oxo-1-PyrrolidinylMethyl-4'-2-Oxazolyl11'-Biphenyl-2-Sulfonamide And Salts Thereof

摘要

Endo useful as endothelin antagonists N - [[2 '- [[(4,5-dimethyl-3-isoxazolyl) amino] sulfonyl] -4- (2-oxazolyl) [1,1'-biphenyl] 2-yl] methyl] -N-3,3-trimethyl butane amide and N- (4,5- dimethyl-3-isoxazolyl) -2 '- [(3,3-dimethyl-2-oxo -1 -pyrrolidinyl) methyl] -4 '- (2-oxazolyl) [1,1'-biphenyl] -2-sulfonamide compounds and their salts.