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23-32- 23-DIHYDROFURO32-PYRIDIN PREPARATION AND APPLICATION THEREOF IN THERAPY
23-32- 23-DIHYDROFURO32-PYRIDIN PREPARATION AND APPLICATION THEREOF IN THERAPY
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机译:23- [32-] 23-二氢呋喃[32-]吡啶的制备及其在治疗中的应用
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摘要
The present invention R 1 is a hydrogen atom, (C 1 -C 6) alkyl or phenyl (C 1 -C 4) alkyl group; R 2 represents a hydrogen atom or an alkyl group (C 1 -C 6); R 3, R 4 and R 5 are, each independently, a hydrogen or halogen atom or a trifluoromethyl, cyano, hydroxy, (C 1 -C 6) alkyl or (C 1 -C 6) each formula represents an alkoxy group It relates to compounds of I. Results of the biological tests performed on the compounds shows that the compounds of the potent and selective cholinergic ligands for nicotinic receptors operation. These results suggest that the compounds can in particular be used for treatment and prevention of central nervous system (CNS), diseases related to dysfunction of the nicotinic receptors operation of GI.; (Formula I)
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