SYNTHESIS OF INDOLES BY DEHYDRATION OF INDOLINES.

摘要

By dehydrogenating indolin or other salts, the corresponding indole of the general formula (I) is obtained:;[Wherein, R ¹ and R ³ independently represent hydrogen or an alkyl group having 1 to 4 carbon atoms, R ² represents hydrogen, a methyl group or a carboxyl group, and R ⁴ and R ⁵ independently represent hydrogen, an amino group, a hydroxyl group, or a carbon number 1 Or an alkyl group having 1 to 4 or an alkoxy group having 1 to 4 carbon atoms, or when they are bonded to adjacent carbon atoms, R ⁴ and R ⁵ may together represent an alkylenedioxy group having 1 to 4 carbon atoms. According to this method, pure indole can be obtained in high yield.