首页> 外国专利> -3-4--1234--9--9- Thermodynamically Stable Form of R-3-4-Fluorophenylsulphonylamino-1234-tetrahydro-9H-carbazole-9-propanoic Acid Ramatroban

-3-4--1234--9--9- Thermodynamically Stable Form of R-3-4-Fluorophenylsulphonylamino-1234-tetrahydro-9H-carbazole-9-propanoic Acid Ramatroban

机译:-3-[[4-]]-1234--9--9- R-3-[[4-氟苯基磺酰基]氨基] -1234-四氢-9H-咔唑-9-丙酸Ramatroban的热力学稳定形式

摘要

The present invention is directed to thermodynamically stable modifications of ramatlovan, the active compounds of formula (I). Thermodynamically stable forms are prepared by melting the metastable form followed by recrystallization or inoculating a solution of the metastable active compound with seed crystals in a thermodynamically stable form. Thermodynamically stable active compounds can be used as agents for asthma.
机译:本发明涉及式(I)的活性化合物雷马洛万的热力学稳定的修饰。通过熔融亚稳形式,然后重结晶或用热力学稳定形式的种晶接种亚稳活性化合物的溶液来制备热力学稳定形式。热力学稳定的活性化合物可用作哮喘的治疗剂。

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