IMMUNOSORBENT FOR REMOVAL OF IMMUNE COMPLEX FORMED BY EQUINE IMMUNOGLOBULINS AFTER ADMINISTRATION OF ANTIDIPHTHERIA SERUM AND METHOD OF HEMOSORPTION CARRYING OUT IN DIPHTHERIA TREATMENT

摘要

FIELD: biology, medicine, veterinary science. SUBSTANCE: invention relates to extracorporal methods of effects on body. Invention proposes hemosorbent based on large-grained agarose matrix and recombinant protein G from cells of Streptococcus, group G. Invention proposes method of carrying out the curative hemosorption that involves passing patient blood with administrated curative sera through sorbent - recombinant IgG-binding protein G of Streptococcus, group G, immobilized on agarose matrix. Curative sera are administrated in extracorporal contour immediately before column during all procedure. Immunosorbent provides removal of high-molecular compounds as immune complexes from blood circulatory system. EFFECT: enhanced effectiveness of immuno- -sorbent. 2 cl, 3 tbl