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Manufacture of solid particulates containing chemically-, biologically- or pharmaceutically-active materials, employs rotary atomizer directing droplets into fluids causing them to set

机译:包含化学,生物或药物活性物质的固体颗粒的制造采用旋转雾化器将液滴引导到流体中,使它们凝固

摘要

Liquid (28) containing active(s) is sprayed (50). The droplet trajectory (F) passes through a further fluid (note: this is high in the spraying unit and may be gaseous). Droplets are intercepted and carried away by yet a further liquid (82). At the end of the trajectory this liquid moves at an angle alpha with respect to the trajectory (F). Droplet solidification to particles (86) is assisted by the liquid (82). An Independent claim is included for corresponding plant and its variants. Preferred features: The liquid (82) moves as a curtain, which is entered by the sprayed droplets. The sprayer projects droplets radially in several directions. The moving liquid medium surrounds the sprayer. The sprayer is rotated about its longitudinal axis when operational. The liquid (82) moves almost vertically. The angle alpha is 20 deg -60 deg , preferably 75 deg -115 deg . Trajectory length is 2-100 cm, preferably 5-20 cm. The sprayer is heated and the temperature of the liquid (82) is controlled. The liquid is a coolant. Both surrounding fluids are coolants. The fluid (82) is water, or a reagent setting the droplets by chemical reaction. Solidification produces a gel.
机译:喷雾(50)含有活性物质的液体(28)。液滴轨迹(F)通过另一种流体(注意:在喷涂单元中该流体很高,可能是气态的)。液滴被另一液体拦截并带走(82)。在轨迹的末端,该液体相对于轨迹(F)以角度α移动。液体(82)辅助液滴固化成颗粒(86)。包括对应植物及其变体的独立权利要求。优选的特征:液体(82)以帘的形式运动,被喷雾的液滴进入。喷雾器沿多个方向径向投射液滴。移动的液体介质围绕喷雾器。操作时,喷涂机绕其纵轴旋转。液体(82)几乎垂直移动。角度α为20度-60度,优选为75度-115度。弹道长度是2-100厘米,最好是5-20厘米。喷雾器被加热并且液体(82)的温度被控制。液体是冷却剂。周围的两种液体都是冷却剂。流体(82)是水或通过化学反应使液滴凝结的试剂。凝固产生凝胶。

著录项

  • 公开/公告号DE19923628A1

    专利类型

  • 公开/公告日2000-11-23

    原文格式PDF

  • 申请/专利权人 HUETTLIN HERBERT;

    申请/专利号DE1999123628

  • 发明设计人 BAUER KURT HEINZ;HUETTLIN HERBERT;

    申请日1999-05-22

  • 分类号B01J2/02;A61J3/00;

  • 国家 DE

  • 入库时间 2022-08-22 01:10:29

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