Skin-friendly active substance patch for transdermal administration of non-steroidal anti-inflammatory drugs

摘要

Active ingredient-containing matrix plaster for the controlled delivery of non-steroidal anti-inflammatory drugs to the skin, consisting of a flexible cover layer and an active ingredient-containing, water-insoluble, pressure-sensitive adhesive matrix, characterized in that the pressure-sensitive adhesive matrix is free of mineral oils and adhesive resins and is composed of DOLLAR A a) synthetic scaffold polymers on the Basis of polyisobutylene to 25 to 90 wt .-%, DOLLAR A b) amorphous poly-alpha-olefin to 5 to 40 wt .-%, DOLLAR A c) from an insoluble, hydrophilic filler with an average grain size of less than 100 mum to 10 to 60 wt .-% and DOLLAR A d) a drug to 0.001 to 20 wt .-%.