LIPID PROFILING OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDS) ON PROSTATE CANCER CELL LINES WITH TOF-SIMS AND DESI-MS

摘要

Prostate cancer (PCa) is the prime cause of cancer related death in Western men. 1 It is not possible to distinguish indolent and aggressive disease, leading to overtreatment and associated complications. NSAIDs can potentially prevent growth of PCa cells, offering an alternative treatment approach. 2 The response of NSAIDs on PCa cell lines varying in clinical aggression was studied using MSI.