Production of bis-phosphino or -arsino compounds, used as chelating ligands for transition metals, involves reacting di-halo compound with two benzyl-diorganyl-element compounds and hydrogenating the product

摘要

Symmetrical or asymmetrical bis-phosphino, bis-arsino or phosphino-arsino compounds are produced by reacting a dihalo-organic compound with two benzyl-diorganyl-phosphine or -arsine compounds which may or may not be identical and then hydrogenating the product. A process for the production of compounds of formula (V) involves reaction of a compound of formula (I) with a dihalo compound (II) and a compound of formula (III) followed by hydrogenation. Hal-X-Hal (II) R1R2E-X-ER6R7 (V) E = phosphorus or arsenic; X = a bridging group with 1-10 atoms between the atoms of E; R1, R2, R6, R7 = 1-20C alkyl, 3-10C cycloalkyl, aryl or heteroaryl with up to 4 condensed rings, or 7-20C aralkyl (all optionally substituted), or R1, R2 and/or R6, R7 together may form 2-20C alkylene, arylene or heteroarylene groups with up to 4 condensed rings, or 7-20C aralkylene (all optionally substituted; R3-R5 = H, hydroxyl, halogen, acyl, CHO, 1-12C alkyl or 6-12C aryl, with the proviso that R4 and R5 are not both OH; Hal = F, Cl, Br or I; R8-R10 = as defined for R3-R5.