4 - Indole - 1 - y - butyric acid derivatives, their preparation and their use as inhibitors for alpha1 - adrenergic receptors and testosterone 5alpha - reductases

摘要

An indole derivative represented by general formula (1) or a salt thereof, and a pharmaceutical containing the derivative or the salt groups defined in the letter. This compound has the effects of both blocking alpha 1-adrenergic receptors and inhibiting testosterone 5 alpha -reductases, and is useful as a remedy and/or a preventive for diseases caused by dihydrotestosterone overproduction, such as prostatic hypertrophy, and diseases accompanying the same, such as urination disorder, male-pattern alopecia, acne and so forth.