derivatives of asiatica - acidity with a modified a ring

摘要

PCT No. PCT/KR97/00240 Sec. 371 Date May 25, 1999 Sec. 102(e) Date May 25, 1999 PCT Filed Nov. 27, 1997 PCT Pub. No. WO98/23575 PCT Pub. Date Jun. 4, 1998Asiatic acid derivatives having a modified A-ring, as represented by formula 1 are disclosed. Pharmaceutical compositions and methods of treating cancer and hepatotoxicity utilizing compounds of formula 1 are also disclosed.