A biomaterial for use as a marker for magnetic resonance imaging consists of a hydrophilic polymer filled with homogeneously distributed superparamagnetic iron oxide particles complexed with a hydrophilic polymer

摘要

A biomaterial constituted from at least one hydrophilic polymer filled with superparamagnetic iron oxide particles complexed with an identical or different hydrophilic polymer, which are dispersed homogeneously and without aggregations in the biomaterial polymer. The material presents a different MRI signal from non-filled biomaterial and from the biological environment in which it is located An Independent claim is included for a method of preparation of the claimed material by mixing into an aqueous solution of hydrophilic monomers particles of superparamagnetic iron oxide complexed with a hydrophilic polymer and polymerizing so as to obtain a polymer in which the iron oxide particles are homogeneously distributed