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Imidazoamp;lsqb;5,1-bamp;rsqb;thiazol-3-yl carbapenem antimicrobials

机译:咪唑/ lsqb; 5,1-b]噻唑-3-基碳青霉烯抗微生物药

摘要

Compounds of formula (I) and compounds of formula (II) which have potent antimicrobial activity against a wide range of bacteria including Gram-positive bacteria and Gram-negative bacteria as well as heve potent antimicrobial activity against various &bgr;-lactamase-producing bacteria, MRSA, and resistant Pseudomonas aeruginosa and are very stable against DHP-1.
机译:具有针对多种细菌(包括革兰氏阳性细菌和革兰氏阴性细菌)的有效抗菌活性以及对多种产生内酰胺酶的高效抗菌活性的式(I)化合物和式(II)化合物,MRSA和铜绿假单胞菌耐药,对DHP-1非常稳定。 <图像文件=“ US06180622-20010130-C00001.GIF” id =“ EMI-C00001” imgContent =“ undefined” imgFormat =“ GIF” />

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