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Method for preparing malonate methylidene nanoparticles, nanoparticles optionally containing one or several biologically active molecules

机译:丙二酸酯亚甲基纳米颗粒的制备方法,任选地包含一种或几种生物活性分子的纳米颗粒

摘要

The invention relates to a method for the preparation of nanoparticles formed from a random polymer of at least one compound of formula (I) ;in which;A represents a ;group or a ;group;;R1 and R2, identical or different, represents a linear or branched C1-C6 alkyl group;;n1, 2, 3, 4 or 5,;characterised in that the monomer is dissolved beforehand in a water-miscible aprotic organic solvent forming, with the polymerisation medium, a non-solvent mixture of the polymer formed.
机译:由至少一种式(I)化合物的无规聚合物形成的纳米粒子的制备方法技术领域本发明涉及一种由至少一种式(I)的化合物的无规聚合物形成的纳米粒子的制备方法。<化学名称=” CHEM-US-00001“> <图像文件=” US06211273-20010403-C00001.GIF “ imgContent =” undefined“ imgFormat =” GIF“ /> ;其中; A代表 <图像文件=“ US06211273-20010403-C00002.GIF” imgContent =“ undefined” imgFormat = “ GIF” /> ExternalFileRef file =“ US06211273-20010403-C00002.MOL” id =“ CHEMMOL-00002” /> < / Chemistry>;组或 <图像文件=“ US06211273-20010403-C00003.GIF” imgContent =“ undefined” imgFormat =“ GIF” /> ; group ;; R 1 和R 2 相同或不同,表示线性或分支的C 1 -C 6 烷基; n1、2、3、4或5;其特征在于,单体预先溶解在与水混溶的非质子有机溶剂中,与聚合介质形成聚合物的非溶剂混合物形成。

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