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SH2-containing inositol-phosphatase

机译:含SH2的肌醇磷酸酶

摘要

Novel SH2-containing inositol-phosphatase which has a src homology 2 (SH2) domain and exhibits phosphoIns-5-ptase activity, and nucleic acid molecules encoding the novel protein are disclosed. The invention also relates to methods for identifying substances which affect the binding of the protein to Shc and/or its phosphoIns-5-ptase activity and methods for screening for agonists or antagonists of the binding of the protein and Shc.
机译:具有src同源性2(SH2)结构域并表现出phosphoIns-5-ptase活性的新型含SH 2的肌醇磷酸酶,并且公开了编码该新型蛋白的核酸分子。本发明还涉及鉴定影响蛋白质与Shc和/或其磷酸化Ins-5-ptase活性结合的物质的方法,以及筛选蛋白质与Shc结合的激动剂或拮抗剂的方法。

著录项

  • 公开/公告号US6218162B1

    专利类型

  • 公开/公告日2001-04-17

    原文格式PDF

  • 申请/专利权人 KRYSTAL GERALD;

    申请/专利号US19960664962

  • 发明设计人

    申请日1996-06-14

  • 分类号C12N91/60;C07K140/00;

  • 国家 US

  • 入库时间 2022-08-22 01:04:35

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