Method for inactivating non-enveloped viral contaminants with a photosensitizer by increasing viral permeability to the photosensitizer

摘要

A method is presented for inactivating non-enveloped viruses that may be contaminating a biological solution or suspension by mixing the solution or suspension with a photosensitizer to form a mixture, adjusting the operating conditions of the mixture so as to increase the permeability of the viruses to the photosensitizer, and then irradiating the adjusted mixture.