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A method for simultaneous identification of novel biological targets and drug discovery lead structures
A method for simultaneous identification of novel biological targets and drug discovery lead structures
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机译:同时识别新型生物靶标和药物发现前导结构的方法
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摘要
The combinatorial screening assays and detection methods of the present invention encompass highly diversified libraries of compounds which act as fingerprints to allow for the identification of specific molecular differences existing between biological samples. The specific molecular differences identified by the combinatorial screening assay and detection methods of the present invention are potential targets for diagnosis and development therapeutics. The methods of the invention can be used in diagnostics, drug discovery, as well as genomics and proteomics. Figure (1) which is illustrative of the methods of the invention shows the interaction between molecular probes described in Table II and a human serum sample.
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