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Use of monocyte-derived cells, antigens and antibodies to optimally induce immunotherapeutic effects
Use of monocyte-derived cells, antigens and antibodies to optimally induce immunotherapeutic effects
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机译:单核细胞来源的细胞,抗原和抗体的使用,以最佳地诱导免疫治疗作用
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摘要
The invention relates to monocyte derived cells, in a purified form and substantially free of contaminants, presenting antigenic epitopes on their membranes after interiorization and processing of at least an antigen-antibody complex formed between an antigen and an antibody, under appropriate conditions, said epitopes corresponding to proteolytic degradation products of said antigen, with said antibody being directed against a tumor or against an infectious agent, and with said antigen being fragments of tumor or of infectious agent, including membranes or tumor apoptotic bodies, or purified tumor or infectious antigens or being recombinant tumor or infectious antigens.
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