Inorganic nitrite and organic acids combined as topical antiviral compositions

摘要

The present invention provides for the use in the manufacture of a topical medicament for the in vivo potentiation of the immune system during a viral skin infection resultant from virus replication in the epidermis, of a topical formulation comprising a source of nitrogen oxides, characterized in that the source of nitrogen oxides is produced when a pharmaceutically acceptable acidifying agent and a pharmaceutically acceptable donor of nitrogen oxides or a precursor therefor are brought into intimate contact at a site of biological action. The invention also provides delivery systems for the topical medicament.