HUMAN DNA LIGASE IV

摘要

PROBLEM TO BE SOLVED: To provide a human DNA ligase IV polypeptide, to provide a DNA (RNA) encoding such a polypeptide, and a method for producing such a polypep tide by gene recombination technique.;SOLUTION: A method for using the human DNA ligase IV polypeptide through a gene therapy in order to treat disorders associated with the deletion of such a polypeptide, the 2nd objective method for using such a polypeptide for therapies for killing antagonists to such a polypeptide and undesirable cells, and the 3rd objective diagnostic method for detecting a DNA ligase IV gene mutant, are provided respectively.;COPYRIGHT: (C)2002,JPO