METHOD FOR PREPARING BIOSENSOR PROTEIN CAPABLE OF CONTROLLING FLUORESCENT PROPERTY OF GREEN FLUORESCENT PROTEIN, AND BIOSENSOR PROTEIN PREPARED BY THE ABOVE METHOD

摘要

PROBLEM TO BE SOLVED: To provide a method for preparing biosensor protein capable of controlling a fluorescent property of a green fluorescent protein by modifying the structure of the green fluorescent protein.;SOLUTION: This objective protein is (1) a modified green fluorescent protein obtained by modifying the structure of the above protein by cleaving the amino acid sequence of the green fluorescent protein in the vicinity of the hot spot amino acid residue influencing the fluorescent property of (2) a biosensor protein containing a functional molecule that functions so as to change the fluorescent property by changing the three-dimensional structure of the above modified green fluorescent protein by transmitting the change of the three-dimensional structure of itself to the above modified green fluorescent protein.;COPYRIGHT: (C)2002,JPO