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Use of CD25 binding molecules in the treatment of rheumatoid arthritis or skin diseases

机译:CD25结合分子在类风湿关节炎或皮肤病治疗中的用途

摘要

Use of a CD25 binding molecule which comprises at least one antigen binding site comprising at least one domain which comprises in sequence, the hypervariable regions CDR1, CDR2 and CDR3; said CDR1 having the amino acid sequence Arg-Tyr-Trp-Met-His, said CDR2 having the amino acid sequence Ala-Ile-Tyr-Pro-Gly-Asn-Ser-Asp-Thr-Ser-Tyr-Asn-Gln-Lys-Phe-Glu-Gly, and said CDR3 having the amino acid sequence Asp-Tyr-Gly-Tyr-Tyr-Phe-Asp-Phe, in the treatment of rheumatoid arthritis or inflammatory or hyperproliferative skin diseases.
机译:包含至少一个抗原结合位点的CD25结合分子的用途,该抗原结合位点包括至少一个结构域,该结构域依次包含高变区CDR1,CDR2和CDR3;所述具有氨基酸序列Arg-Tyr-Trp-Met-His的CDR1,所述具有氨基酸序列Ala-Ile-Tyr-Pro-Gly-Asn-Ser-Asp-Thr-Ser-Tyr-Asn-Gln-的CDR2。 Lys-Phe-Glu-Gly,以及具有氨基酸序列Asp-Tyr-Gly-Tyr-Tyr-Phe-Asp-Phe的所述CDR3,用于治疗类风湿性关节炎或炎性或过度增生的皮肤病。

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