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Polyketide synthase encoded by a methymycin/pikromycin biosynthetic gene cluster
Polyketide synthase encoded by a methymycin/pikromycin biosynthetic gene cluster
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机译:甲霉素/匹霉素生物合成基因簇编码的聚酮化合物合酶
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摘要
A novel pathway for the synthesis of polyhydroxyalkanoates is provided. A method of synthesizing a recombinant polyhydroxyalkanoate monomer synthase is also provided. These recombinant polyhydroxyalkanoate synthases are derived from multifunctional fatty acid synthases or polyketide synthases and generate hydroxyacyl acids capable of polymerization by a polyhydroxyalkanoate synthase. Also provided is a biosynthetic gene cluster for methymycin and pikomycin as well as a biosynthetic gene cluster for desosamine.
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