Presentation of hydrophobic antigens to T-cells by CD1 molecules

摘要

Provided are CD-1 presented antigens, compositions, cells, inhibitors and methods relating to the use of hydrophobic antigen presentation by CD1 molecules, including: ;methods for detecting the presence of a CD1-presented hydrophobic antigen in a sample; ;methods for isolating such CD1-presented antigens and the isolated antigens; ;vaccines containing CD1-presented antigens and vaccination methods; ;methods of blocking CD1 antigen presentation; ;methods of identifying and/or isolating CD1 blocking agents and the isolated CD1 blocking agents; ;methods of inducing CD1 expression; and ;T-cells for use in the methods disclosed herein.