首页>
外国专利>
Superoxide dismutase or superoxide dismutase mimic coating for an intracorporeal medical device
Superoxide dismutase or superoxide dismutase mimic coating for an intracorporeal medical device
展开▼
机译:用于体内医疗设备的超氧化物歧化酶或超氧化物歧化酶模拟涂层
展开▼
页面导航
摘要
著录项
相似文献
摘要
A method of providing a therapeutic, diagnostic or lubricious hydrophilic coating on an intracorporeal medical device and the coated device produced thereby, wherein the coating is durable. In one embodiment, the coating comprises a polymerized base coat and a top coat having a therapeutic, diagnostic or hydrophilic agent, where the base coat has a binding component which binds to the top coat, and a grafting component which binds to the binding component and adheres to the device. In another embodiment, the coating comprises a blend of an agent, a grafting component, and salt. In one embodiment, the therapeutic agent is superoxide dismutase or a superoxide dismutase mimic. The coating of the invention may be applied to a medical device with a polymeric surface such as a polymeric catheter, or a metal device such as a stent coated with a polymeric primer or without a primer.
展开▼