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Bovine cells expressing adenovirus essential functions for propagation of recombinant adenoviral vectors
Bovine cells expressing adenovirus essential functions for propagation of recombinant adenoviral vectors
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机译:表达重组腺病毒载体的腺病毒必需功能的牛细胞
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摘要
The invention provides cell lines capable of supporting the replication of a defective recombinant virus vector. In one aspect, bovine cell lines expressing adenovirus E1 functions are provided. The cell lines are useful for the propagation of adenovirus vectors with mutations and/or deletions in E1 and other essential regions of the adenovirus genome.
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