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Screening novel human phosphodiesterase IV isozymes for compounds which modify their enzymatic activity
Screening novel human phosphodiesterase IV isozymes for compounds which modify their enzymatic activity
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机译:筛选新型人磷酸二酯酶IV同工酶以寻找可改变其酶活性的化合物
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摘要
This invention relates to novel nucleic acid sequences encoding three novel human phosphodiesterase (hPDE IV) isozymes. It also relates to polypeptides encoded by such sequences. This invention also relates to an assay method for detecting the presence of such novel isozymes in human cells, and to a method of identifying compounds or other substances that inhibit or modify the activity of such isozymes.
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