2,4,6-trisubstituted pryridines with estrogenic activity and methods for the solid phase synthesis thereof

摘要

The present invention relates to novel substituted pyridine compounds of Formula (I) ;wherein the moiety Z, R¹, R² and R³ are as herein defined, having estrogenic activity, to processes for their preparation, to a combinatorial library and solid phase methods for preparing libraries of the compounds, to utilizing libraries of the compounds for drug discovery, to methods of treatment and to pharmaceutical compositions thereof.