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Water-soluble extract of asiaticoside and madecassoside from Centella asiatica and isolating method thereof

机译:积雪草积雪草苷和积雪草苷的水溶性提取物及其分离方法

摘要

A water-soluble extract of asiaticoside and madecassoside from Centella asiatica and an isolating method thereof. In the isolating method an aqueous alcohol containing Centella asiatica is subjected to cold-precipitation to obtain an extract. The extract in the aqueous alcohol is treated with a halogenide solvent for layer separation, and then the aqueous layer is extracted with a higher alcohol. The extract in the alcohol layer is washed first with sodium hydroxide and then with water. After being concentrated, the extract is crystallized with ethyl acetate to obtain crystals and the crystals are washed. A method for treating liver cells in a mammal includes administering to a mammal an effective amount of the extract from Centella asiatica containing asiaticoside and madecassoside.
机译:积雪草的积雪草苷和积雪草苷的水溶性提取物及其分离方法。在分离方法中,对含有积雪草的含水醇进行冷沉淀以获得提取物。用卤化物溶剂处理含水醇中的提取物以进行层分离,然后用高级醇提取水层。醇层中的提取物首先用氢氧化钠洗涤,然后用水洗涤。浓缩后,将萃取液用乙酸乙酯结晶,得到晶体,并洗涤晶体。一种在哺乳动物中治疗肝细胞的方法,包括对哺乳动物施用有效量的含积雪草苷和积雪草苷的积雪草提取物。

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