A procedure for preparing alkylated Derivatives of benzoic acid in Ortho position and the use of acid 4-chloro-2 - metilbenzoico, prepared according to the procedure,As an intermediate in the synthesis of N - diaminometilen - 2-methyl-4 - (1 - pirrolil) - 5 - metilsulfonilbenzamida and N - Day

摘要

A procedure for preparing alkylated Derivatives of benzoic acid in Ortho position corresponding to formula (1) wherein a represents a rest dealquilo 1 to 4 c Atoms.Characterised by a reaction of aryl bromide Lafo, as indicated in formula (2) which have the meaning indicated for laformula (1) with a compound of organolithium Reagents and Secondary or TertiaryCO2.The use of acid - 2 - methyl 4-chloro benzoic acid, prepared under the procedimientodescripto,As productointermed Io in the synthesis of N - methyl - 2 - diaminometilen - (1 - pirrolil) - 5 -) - benzamide and N - diaminometilen - 2 - methyl - 5 - Di - (methylsulphonyl) - benzamide.