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A polymorphic form of a Derivative of Maleic acid tiazolidin Dione - 2, 4, a Pharmaceutical Composition and the use of said Polymorph to put it, the manufacture of a medicament
A polymorphic form of a Derivative of Maleic acid tiazolidin Dione - 2, 4, a Pharmaceutical Composition and the use of said Polymorph to put it, the manufacture of a medicament
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机译:马来酸噻唑烷二酮二酮衍生物的多晶型物-2,4,药物组合物以及所述多晶型物的使用,药物的制造
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摘要
A polymorphic form of Maleic acid salt of 5 - [4 - [2 - (n-methyl-n - (2-pyridyl) amino) ethoxy] benzyl] thiazolidine-2,4-dione (Polymorph)Caracterizadoporque provides (i) an infrared Spectrum contains Peaks to 1763, 912, 856 tonnes 709 cm-1, and / or (ii) a Raman Spectrum contains Peaks to 1762, 1.284, 912y 888 cm - 1, and / or (iii) a Spectrum of nuclear magnetic resonance in Solid State 13C containing Peaks to 111.0, 113.6 129.1, 130.9 131.8 119.8,,,, 134,7138,7, 146.5 152.7 157.5, 169,,,5 171.0 178.7 ppm; and / or (iv) an x-ray diffraction Pattern through the Dust (XRPD) that gives reticularescalculadas distances to 5.87, 5.30, 4.69, 4.09, 3.88, 3.61, 3.53 and 346 angstroms; a procedure for preparing such a Compound, a Pharmaceutical composition containing Said compound and use of said compound in Medicine.
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