Caprolactamas replaced, a process for their preparation, Pharmaceutical compositions containing them, and their use for the preparation of composicionesfarmaceuticas In Treatment of tumors

摘要

1. The term "surrogate caprolactas" herein refers to a formula compound (1), wherein: R1 is C1-6 tar or C3-6 cyclopropyl tar; R2 is C1-6 solution or C1-6 tar; X is C1-12 tar, c2-12 alquenileno or c2-12; m is 0 O1; R3 is C3-8 cyclopropyl compound; Or the aromatic ring system selected from formula (2) to (5),Wherein: R4 is hydrogen, chlorine or methoxy; R5 is hydrogen, chlorine, c1-18 tar or c1-18 alkane; and Z esoorio, sulfur, N-H, on-ch3; or, where feasible, an acceptable drug acid addictive sa n-propane substituted by compounds containing these compounds, Or use these compounds to prepare for drug treatment or cancer screening, and a processing plant to make these compounds