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Manufacture of precursors of hormones, hormone precursor formulation, composition and hormonal application
Manufacture of precursors of hormones, hormone precursor formulation, composition and hormonal application
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机译:激素前体的制造,激素前体制剂,组成和激素应用
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"The manufacture of precursors of hormones, the formulation of hormonal precursors, hormonal composition and application.This invenu00e7u00e3otem aimed to provide new precursors hormonaiscaracterizados by general formula norandrostanodiol (estranodiol) enorandrostanodiona (estranodiona) called here phdo # 1 HPAThe # 2 respectively, where each molecule of phdo # 1 ephdo # 2 is indicated by V ~ n ~, n = the number of 1 to 37),Being vconstituu00edda possible introductions of several groups funcionaischamados of substituents s ~ n ~ where n can vary from 1 to 9 erepresentam the following possible changes or additions nasmolu00e9culThe basic (norandrostanodiol and norandrostanodiona): s1u00e9 an unsaturation connecting carbon carbon 1 and 2, S2 is in a position where umoxigu00eanio should meet the carbon 2.S3 is a desaturation between carbon 4 and the carbon 5, S4 is umhalogu00eanio connected to carbon 4, S5 is a halogen bonded aocarbono 5S6 is a halogen bonded to carbon 4 and the other ligadoao carbon 5 at the same time, S7 is a methyl group (CH3) ligadoao carbon 19, S8 is a hydroxymethylene attached to carbon 2.The methyl group attached to the carbon S9 is 2.To his conversu00e3opelo human organism active derivatives of testosterone compropriedades the most diverse and covering the greater part of all basic molecular asestruturas allowing estThe conversion peloorganismo human.Also refers to the application of these comomu00e9todo effective for the production line of detestosterona endogenous derivatives for these basic structures and application paraterapias replacement andru00f3geAnd in doenu00e7asdegenerativas.
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