Cytochrome p450 monooxygenase, nucleic acid sequence, expression construct, vector, recombinant microorganism, process for the microbiological oxidation of a mono- or polynuclear aromatic compound n- or s-heterocyclic, process for the microbiological production of indigo and / or indirectubin, bioreactor , use of a cytochrome p450 monooxygenase, a vector, or a microorganism, and use of a microorganism that produces cytochrome p450 indole oxidizer

摘要

"CYTOCHROME P450 MONOOXYGENASE, NUCLEIC ACID SEQUENCE, EXPRESSION CONSTRUCT, VECTOR, RECOMBINANT MICROORGANISM, PROCESS FOR THE MICROBIOLOGICAL OXIDATION OF A MONO OR POLINUCOUS AROMATIC COMPOUND, INDICATIVE OR HYDRO-ORGANIC WATER PROTECTION BIORREACTOR, USE OF A CITOCHROME P450 MONOOXYGENASE, OF A VECTOR, OR OF A MICROORGANISM, AND USE OF A MICROORGANISM THAT PRODUCES CYTOCHROME P450 INDOL OXIDANT ". The invention relates to the new cytochrome P450 monooxygenases comprising a modified substrate specificity, the nucleotide sequences that encode them, the vectors and expression constructs containing these sequences, and the microorganisms transformed with them. The invention also relates to methods for microbiologically oxidizing different organic substrates, such as methods for producing indigo and indirectubin.