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Veterinary formulation for administering a water-insoluble drug to a target animal through a water distribution system

机译:通过水分配系统将水不溶性药物施用于目标动物的兽用制剂

摘要

"VETERINARY FORMULATION FOR THE ADMINISTRATION OF AN INSOLIBLE DRUG IN WATER TO A TARGET ANIMAL THROUGH A WATER DISTRIBUTION SYSTEM". This invention relates to a method for the preparation of a suspoemulsion formulation, which can be easily produced on an industrial scale and which allows the reproducible and effective administration of one or more water-insoluble veterinary drugs through drug delivery systems. Water. The water-insoluble veterinary drug, in finely ground form, is dispersed in a water-miscible liquid, followed by homogenization of this system in a water phase. To facilitate the preparation of a stable formulation, one or more stabilizing agents such as emulsifiers, thickeners, antioxidants and antimicrobials can be used. The resulting suspoemulsion shows excellent stability in long-term storage and good stability "in use" after dilution in a container and throughout handling and transportation in the water distribution system.
机译:“通过配水系统将不溶性药物管理到目标动物的兽医配方”。本发明涉及一种制备悬浮乳剂的方法,该悬浮乳剂可以容易地以工业规模生产,并允许通过药物输送系统可再现和有效地给药一种或多种水不溶性兽药。水。将精细研磨形式的水不溶性兽药分散在与水混溶的液体中,然后将该系统在水相中匀浆。为了促进稳定制剂的制备,可以使用一种或多种稳定剂,例如乳化剂,增稠剂,抗氧化剂和抗微生物剂。所得的悬浮乳液在长期储存中显示出极好的稳定性,在容器中稀释后以及在配水系统中的整个处理和运输过程中,都显示出良好的“使用中”稳定性。

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