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Veterinary formulation for administration of water-insoluble drugs through a water distribution system to target animals
Veterinary formulation for administration of water-insoluble drugs through a water distribution system to target animals
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机译:通过水分配系统向目标动物施用水不溶性药物的兽用制剂
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摘要
This invention concerns a method for the preparation of a suspoemulsion formulation, which can be easily produced on an industrial scale and which allows the reproducible and effective administration of one or more water-insoluble veterinary drugs through water distribution systems. The water-insoluble veterinary drug, in finely ground form, is dispersed in a water immiscible liquid, followed by homogenization of this system into a water phase. To facilitate the preparation of a stable formulation, one or more stabilizing agents such as emulsifiers, thickeners, anti-oxidants and anti-microbials can be used. The resulting suspoemulsion shows excellent long term storage stability and a good in use stability after dilution in a vessel and during all handling and transport in the water distribution system.
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